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Takahiro Ochiya Selected Research

atelocollagen

1/2020MicroRNA-124a inhibits endoderm lineage commitment by targeting Sox17 and Gata6 in mouse embryonic stem cells.
9/2015Targeted Knockdown of the Kinetochore Protein D40/Knl-1 Inhibits Human Cancer in a p53 Status-Independent Manner.
1/2010Systemic delivery of synthetic microRNA-16 inhibits the growth of metastatic prostate tumors via downregulation of multiple cell-cycle genes.
6/2008An siRNA against JC virus (JCV) agnoprotein inhibits JCV infection in JCV-producing cells inoculated in nude mice.
2/2007Atelocollagen-mediated drug discovery technology.
10/2006Atelocollagen-mediated systemic DDS for nucleic acid medicines.
9/2006Intratumor injection of small interfering RNA-targeting human papillomavirus 18 E6 and E7 successfully inhibits the growth of cervical cancer.
8/2005Efficient delivery of small interfering RNA to bone-metastatic tumors by using atelocollagen in vivo.
7/2004Atelocollagen-mediated synthetic small interfering RNA delivery for effective gene silencing in vitro and in vivo.
3/2004Potential of atelocollagen-mediated systemic antisense therapeutics for inflammatory disease.
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Takahiro Ochiya Research Topics

Disease

176Neoplasms (Cancer)
01/2022 - 03/2002
43Neoplasm Metastasis (Metastasis)
01/2022 - 06/2005
38Breast Neoplasms (Breast Cancer)
09/2021 - 09/2008
17Carcinogenesis
01/2021 - 03/2002
13Prostatic Neoplasms (Prostate Cancer)
09/2021 - 08/2005
12Stomach Neoplasms (Stomach Cancer)
09/2021 - 06/2005
11Sarcoma (Soft Tissue Sarcoma)
09/2021 - 02/2012
11Lung Neoplasms (Lung Cancer)
09/2021 - 11/2013
9Infections
11/2019 - 06/2008
8Hepatocellular Carcinoma (Hepatoma)
01/2022 - 02/2006
8Liver Neoplasms (Liver Cancer)
09/2021 - 11/2009
8Ovarian Neoplasms (Ovarian Cancer)
09/2021 - 01/2016
7Carcinoma (Carcinomatosis)
12/2021 - 11/2003
7Osteosarcoma (Osteogenic Sarcoma)
08/2021 - 06/2011
7Fibrosis (Cirrhosis)
03/2021 - 04/2005
7Liver Diseases (Liver Disease)
02/2020 - 07/2007
6Urinary Bladder Neoplasms (Bladder Cancer)
01/2022 - 03/2013
5Colorectal Neoplasms (Colorectal Cancer)
11/2021 - 12/2009
5Liver Cirrhosis (Hepatic Cirrhosis)
03/2021 - 01/2011
5Adenocarcinoma
12/2020 - 12/2006
5Inflammation (Inflammations)
01/2020 - 03/2004
5Virus Diseases (Viral Diseases)
02/2013 - 02/2007
4Colonic Neoplasms (Colon Cancer)
12/2021 - 12/2012
4Dementia (Dementias)
11/2021 - 01/2019
4Alzheimer Disease (Alzheimer's Disease)
10/2021 - 01/2013
4Disease Progression
02/2020 - 03/2013
3Biliary Tract Neoplasms (Biliary Tract Cancer)
09/2021 - 11/2019
3Hypoxia (Hypoxemia)
01/2021 - 10/2012
3Adenocarcinoma of Lung
01/2020 - 08/2014
3Glioma (Gliomas)
12/2019 - 06/2007
3Hepatitis B
01/2019 - 11/2013
3Synovial Sarcoma (Synovioma)
11/2018 - 11/2017
3Ascites
01/2017 - 08/2006
3Liver Failure
01/2012 - 02/2010
2Multiple Myeloma
01/2022 - 03/2018
2Pancreatic Neoplasms (Pancreatic Cancer)
09/2021 - 01/2018
2Brain Neoplasms (Brain Tumor)
09/2021 - 12/2019
2Esophageal Neoplasms (Esophageal Cancer)
09/2021 - 01/2019
2Ovarian Epithelial Carcinoma
10/2020 - 04/2020
2Head and Neck Neoplasms (Head and Neck Cancer)
04/2020 - 02/2018
2Esophageal Squamous Cell Carcinoma
02/2020 - 01/2019
2Chronic Hepatitis C
11/2019 - 01/2012
2Lymphatic Metastasis
01/2019 - 11/2003
2Chronic Hepatitis B
01/2019 - 01/2012
2Gastrointestinal Neoplasms (Gastrointestinal Cancer)
01/2019 - 10/2018
2Lung Diseases (Lung Disease)
10/2018 - 02/2013
2Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2017 - 05/2016
2Chronic Obstructive Pulmonary Disease (COPD)
10/2016 - 01/2015

Drug/Important Bio-Agent (IBA)

132MicroRNAs (MicroRNA)IBA
10/2022 - 11/2009
58Biomarkers (Surrogate Marker)IBA
10/2022 - 07/2006
28Proteins (Proteins, Gene)FDA Link
01/2021 - 07/2002
24Pharmaceutical PreparationsIBA
01/2021 - 08/2006
20Small Interfering RNA (siRNA)IBA
05/2016 - 07/2004
14Biological ProductsIBA
11/2021 - 03/2002
11atelocollagenIBA
01/2020 - 11/2003
10Messenger RNA (mRNA)IBA
09/2020 - 03/2004
7RNA (Ribonucleic Acid)IBA
01/2021 - 07/2014
6Docetaxel (Taxotere)FDA Link
06/2020 - 09/2008
6ribophorinIBA
06/2015 - 01/2013
5Peptides (Polypeptides)IBA
12/2021 - 01/2013
5AntibodiesIBA
12/2021 - 04/2014
5CytokinesIBA
01/2021 - 10/2012
5Cisplatin (Platino)FDA LinkGeneric
11/2020 - 02/2015
5DNA (Deoxyribonucleic Acid)IBA
09/2020 - 07/2013
5Therapeutic UsesIBA
06/2020 - 04/2005
5LuciferasesIBA
01/2017 - 07/2004
4InterferonsIBA
03/2021 - 02/2012
4PlatinumIBA
11/2020 - 04/2015
4LigandsIBA
01/2019 - 07/2006
3Membrane Proteins (Integral Membrane Proteins)IBA
12/2021 - 06/2015
3Antiviral Agents (Antivirals)IBA
01/2021 - 01/2019
3Long Noncoding RNAIBA
09/2020 - 07/2018
3LipidsIBA
09/2020 - 04/2016
3Circulating MicroRNAIBA
02/2020 - 10/2010
3OligonucleotidesIBA
04/2019 - 03/2004
3ResveratrolIBA
05/2018 - 01/2012
3Antineoplastic Agents (Antineoplastics)IBA
10/2016 - 08/2006
3TransferasesIBA
02/2015 - 05/2014
3Hyaluronic Acid (Hyaluronan)IBA
07/2014 - 09/2010
3Tumor Biomarkers (Tumor Markers)IBA
03/2014 - 02/2006
2Programmed Cell Death 1 ReceptorIBA
01/2021 - 02/2020
2Hormones (Hormone)IBA
01/2021 - 01/2020
2Conditioned Culture MediaIBA
01/2021 - 11/2018
2AndrogensIBA
01/2021 - 06/2008
2CateninsIBA
01/2021 - 12/2014
2Phenobarbital (Luminal)FDA Link
01/2019 - 06/2015
2ChemokinesIBA
01/2019 - 10/2012
2pazopanibFDA Link
11/2018 - 01/2018
2Azacitidine (5 Azacytidine)FDA Link
01/2018 - 01/2018
2A-Form DNA (A-DNA)IBA
03/2017 - 05/2004
2Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
01/2017 - 06/2015

Therapy/Procedure

63Therapeutics
01/2021 - 09/2006
8Transplantation
01/2019 - 04/2005
6Drug Therapy (Chemotherapy)
01/2022 - 04/2014
5RNAi Therapeutics
03/2015 - 01/2012
3Intravenous Injections
01/2017 - 06/2011
2Radiotherapy
01/2022 - 04/2008
2Adjuvant Chemotherapy
01/2020 - 05/2016
2Aftercare (After-Treatment)
01/2020 - 11/2019
2Cell Transplantation
01/2019 - 01/2018